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1

A Practical Synthesis of a Hydroxylated Sesquiterpene Coumarin 10’R-Acetoxy-11’-hydroxyumbelliprenin by Regioselective Dihydroxylation

Akaji, Kenichi, Hattori, Yasunao, Kinami, Genki, Teruya, Kenta, Nosaka, Kazuto, Kobayashi, Kazuya

Journal:

Year:

2013

Language:

english

File:

PDF, 680 KB

english, 2013

2

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study

Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Kiso, Yoshiaki, Kawasaki, Yuko, Chen, Shen-En, Naser-Tav

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

3

A Thermodynamic Preference of Chiral N -Methanesulfonyl and N -Arenesulfonyl 2,3- cis -3-Alkyl-2-Vinylaziridines over Their 2,3- Trans -Isomers: Useful Palladium(0)-Catalyzed Equilibration Reactions for the Synthesis of ( E )-Alkene Dipeptide Isosteres

Ibuka, Toshiro, Mimura, Norio, Aoyama, Hiroshi, Akaji, Masako, Ohno, Hiroaki, Miwa, Yoshihisa, Taga, Tooru, Nakai, Kazuo, Tamamura, Hirokazu, Fujii, Nobutaka, Yamamoto, Yoshinori

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 760 KB

english, 1997

4

Total synthesis of miraziridine A and identification of its major reaction site for cathepsin B

Hiroyuki Konno, Kanako Kubo, Hidefumi Makabe, Emi Toshiro, Naoyuki Hinoda, Kazuto Nosaka, Kenichi Akaji

Journal:

Year:

2007

Language:

english

File:

PDF, 420 KB

english, 2007

5

Interleukin-1β inhibits long-term potentiation in the CA3 region of mouse hippocampal slices

Hiroshi Katsuki, Satoru Nakai, Yoshikatsu Hirai, Ken-ichi Akaji, Yoshiaki Kiso, Masamichi Satoh

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 283 KB

english, 1990

6

Population structures and spatial patterns of two unpalatable Arisaema species (Araceae) with and without clonal reproduction in a riparian forest intensively grazed by Sika deer

Matsumoto, Tetsuya K., Hirobe, Muneto, Akaji, Yasuaki, Miyazaki, Yuko

Journal:

Journal of Forestry Research

Year:

2018

Language:

english

File:

PDF, 761 KB

english, 2018

7

Studies on peptides. CLXVIII. Syntheses of three peptides isolated from horseshoe crab hemocytes, tachyplesin I, tachyplesin II, and polyphemusin I.

AKAJI, Kenichi, FUJII, Nobutaka, TOKUNAGA, Fuminori, MIYATA, Toshiyuki, IWANAGA, Sadaaki, YAJIMA, Haruaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 714 KB

1989

8

Design and synthesis of a series of serine derivatives as small molecule inhibitors of the SARS coronavirus 3CL protease

Konno, Hiroyuki, Wakabayashi, Masaki, Takanuma, Daiki, Saito, Yota, Akaji, Kenichi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

9

Characteristics of subcortical infarction due to distal MCA penetrating artery occlusion

Suzuki, Kentaro, Aoki, Junya, Tanizaki, Yoshio, Sakamoto, Yuki, Takahashi, Satoshi, Abe, Arata, Kimura, Hiroaki, Kano, Tadashige, Suda, Satoshi, Nishiyama, Yasuhiro, Akaji, Kazunori, Mihara, Ban, Kimu

Journal:

Journal of the Neurological Sciences

Year:

2016

Language:

english

File:

PDF, 812 KB

english, 2016

10

An unusual thermodynamic preference of chiral N-arylsulfonyl cis-3-alkyl-2-vinylaziridines over their trans-isomers: palladium(0)-catalysed equilibration reactions

Mimura, Norio, Ibuka, Toshiro, Akaji, Masako, Miwa, Yoshihisa, Taga, Tooru, Nakai, Kazuo, Tamamura, Hirokazu, Fujii, Nobutaka, Yamamoto, Yoshinori

Journal:

Chemical Communications

Year:

1996

Language:

english

File:

PDF, 259 KB

english, 1996

11

Transferrin-Modified Liposomes Equipped with a pH-Sensitive Fusogenic Peptide: An Artificial Viral-like Delivery System †

Kakudo, Tomoyuki, Chaki, Shinji, Futaki, Shiroh, Nakase, Ikuhiko, Akaji, Kenichi, Kawakami, Toru, Maruyama, Kazuo, Kamiya, Hiroyuki, Harashima, Hideyoshi

Journal:

Year:

2004

Language:

english

File:

PDF, 749 KB

english, 2004

12

Efficient synthesis of peptaibol using a chloroimidazolidium coupling reagent, CIP

Kenichi Akaji, Yasunori Tamai, Yoshiaki Kiso

Journal:

Year:

1997

Language:

english

File:

PDF, 1.53 MB

english, 1997

13

Total synthesis of [L40I, C90A, C109A]-human T-cell leukemia virus type 1 protease

Kenta Teruya, Toru Kawakami, Kenichi Akaji, Saburo Aimoto

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

14

Synthesis of a membrane protein with two transmembrane regions

Takeshi Sato, Toru Kawakami, Kenichi Akaji, Hiroki Konishi, Koji Mochizuki, Toshimichi Fujiwara, Hideo Akutsu, Saburo Aimoto

Journal:

Journal of Peptide Science

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

15

ChemInform Abstract: Simple One-Pot Transformations of Toluene-p-sulfonates of 2,3-Epoxy Alcohols into Allylic Alcohols.

N. FUJII, H. HABASHITA, M. AKAJI, K. NAKAI, T. IBUKA, M. FUJIWARA, H. TAMAMURA, Y. YAMAMOTO

Journal:

Year:

1996

File:

PDF, 28 KB

1996

16

The Optimal Dose of Nicardipine for Enhancement of Indirect Portography

Inoue, Yutaka, Nakamura, Hironobu, Akaji, Hideyo

Journal:

CardioVascular and Interventional Radiology

Year:

1998

Language:

english

File:

PDF, 137 KB

english, 1998

17

The polyphenol (−)-epigallocatechin-3-gallate prevents apoA-I Iowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity

Nakajima, Hiroyuki, Nishitsuji, Kazuchika, Kawashima, Hiroyuki, Kuwabara, Kaori, Mikawa, Shiho, Uchimura, Kenji, Akaji, Kenichi, Kashiwada, Yoshiki, Kobayashi, Norihiro, Saito, Hiroyuki, Sakashita, Na

Journal:

Year:

2015

Language:

english

File:

PDF, 817 KB

english, 2015

18

Prediction of Cerebrovascular Reserve Capacity by Computed Tomography Perfusion Using 320-Row Computed Tomography

Takahashi, Satoshi, Tanizaki, Yoshio, Kimura, Hiroaki, Akaji, Kazunori, Kano, Tadashige, Suzuki, Kentaro, Takayama, Youhei, Kanzawa, Takao, Shidoh, Satoka, Nakazawa, Masaki, Yoshida, Kazunari, Mihara,

Journal:

Journal of Stroke and Cerebrovascular Diseases

Year:

2015

Language:

english

File:

PDF, 749 KB

english, 2015

19

Studies on peptides. CXL Synthesis of human gastrin-releasing polypeptide (hGRP).

KUNO, SUZUMITSU, AKAJI, KENICHI, IKEMURA, OSAMU, MORIGA, MOTOYUKI, AONO, MITSURU, MIZUTA, KAZUHIKO, TAKAGI, ATSUSHI, YAJIMA, HARUAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 983 KB

1986

20

Studies on peptides. CXXXVI. Solution-phase synthesis of a 37-residue peptide amide corresponding to the entire amino acid sequence of human calcitonin gene-related peptide (hCGRP).

FUJII, NOBUTAKA, OTAKA, AKIRA, FUNAKOSHI, SUSUMU, NOMIZU, MOTOYOSHI, AKAJI, KENICHI, YAJIMA, HARUAKI, YAMAMOTO, ITSUO, TORIZUKA, KANJI, KITAGAWA, KOUKI, AKITA, TADASHI, ANDO, KENSHI, KAWAMOTO, TATSUHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 877 KB

1986

21

Synthesis of a hentetracontapeptide amide corresponding to the entire amino acid sequence of human corticotropin releasing factor (hCRF).

Yajima, Haruaki, Fujii, Nobutaka, Nomizu, Motoyoshi, Watanabe, Kazuhide, Akaji, Kenichi, Shimokura, Masanori, Katakura, Shinichi, Shono, Fumiaki, Tsuda, Masafumi, Yoshitake, Akira

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 386 KB

1984

22

Survival and growth of Fagus crenata seedlings in relation to biological and microtopographical factors in a cool temperate broadleaf forest

Akaji, Yasuaki, Hirobe, Muneto, Miyazaki, Yuko, Makimoto, Takushi, Kinoshita, Shu, Hattori, Itsuka, Sakamoto, Keiji

Journal:

Journal of Forest Research

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

23

1P083 Evaluation of inter-molecular interaction of a protein in highly concentrated solution investigated by Raman spectroscopy(01E. Protein : Measurement & Analysis,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Akaji, Sakiko, Ota, Chikashi, Noguchi, Shintaro, Tsumoto, Kohei

Journal:

Seibutsu Butsuri

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

24

A novel amphipathic cell-penetrating peptide based on the N-terminal glycosaminoglycan binding region of human apolipoprotein E

Ohgita, Takashi, Takechi-Haraya, Yuki, Nadai, Ryo, Kotani, Mana, Tamura, Yuki, Nishikiori, Karin, Nishitsuji, Kazuchika, Uchimura, Kenji, Hasegawa, Koki, Sakai-Kato, Kumiko, Akaji, Kenichi, Saito, Hir

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2018

Language:

english

File:

PDF, 3.40 MB

english, 2018

25

Occupational Stress in Dental Practice amongst Government-employed and Private Dental Practitioners in Eastern Nigeria: A comparative survey

Chukwuneke, F.N, Akaji, E.A, Okoye, L.O, Ekwueme, O.C, Anyanechi, C.E

Journal:

Tanzania Dental Journal

Year:

2010

File:

PDF, 546 KB

2010

26

Functionalized Glutathione on Chitosan-Genipin Cross-Linked Beads Used for the Removal of Trace Metals from Water

Akaji, Samira R., Dewez, David

Journal:

International Journal of Biomaterials

Year:

2020

File:

PDF, 3.02 MB

2020

27

ChemInform Abstract: One-Pot Transformation of p-Toluenesulfonates of 2,3-Epoxy Alcohols into Allylic Alcohols.

H. HABASHITA, T. KAWASAKI, M. AKAJI, H. TAMAMURA, T. KIMACHI, N. FUJII, T. IBUKA

Journal:

Year:

1998

File:

PDF, 32 KB

1998

28

ChemInform Abstract: KNI-577, a Potent Small-Sized HIV Protease Inhibitor Based on the Dipeptide Containing the Hydroxymethylcarbonyl Isostere as an Ideal Transition-State Mimic

Y. KISO, S. YAMAGUCHI, H. MATSUMOTO, T. MIMOTO, R. KATO, S. NOJIMA, H. TAKAKU, T. FUKAZAWA, T. KIMURA, K. AKAJI

Journal:

Year:

1998

File:

PDF, 29 KB

1998

29

Regioselective double disulfide formation using silylchloride-sulfoxide system

Kenichi Akaji, Kenji Fujino, Tadashi Tatsumi, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 298 KB

english, 1992

30

Chemical Dynamic Kinetic Resolution and S / R Interconversion of Unprotected α-Amino Acids

Takeda, Ryosuke, Kawamura, Akie, Kawashima, Aki, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Akaji, Kenichi, Wang, Shuni, Liu, Hong, Aceña, José Luis, Soloshonok, Vadim A.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 386 KB

english, 2014

31

ChemInform Abstract: Studies on Peptides. Part 141. Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Porcine GIP (Glucose- Dependent Insulinotropic Polypeptide).

SAKURAI, M., AKAJI, K., FUJII, N., MORIGA, M., AONO, M., MIZUTA, K., ADACHI, H., NOGUCHI, M., INOUE, K., HOSOTANI, R., TOBE, T., YAJIMA, H.

Journal:

Year:

1987

File:

PDF, 89 KB

1987

32

Studies on peptides. CXXII. N-Succinimidyl-p-(2-nitrovinyl)-benzoate and its m-isomer, as heterobifunctional conjugatin reagents for immunoassay.

FUJII, NOBUTAKA, HAYASHI, YOSHIO, FUTAKI, SHIROH, AKAJI, KENICHI, YAJIMA, HARUAKI, KITAGAWA, TSUNEHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 570 KB

1984

33

Trimethylacetamidomethyl (Tacm) group. a new protecting group for the thiol function of cysteine.

KISO, Yoshiaki, YOSHIDA, Makoto, FUJIWARA, Yoichi, KOIMURA, Tooru, SHIMOKURA, Masanori, AKAJI, Kenichi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 632 KB

1990

34

Studies on peptides. CLIII. Application of the hard-acid deprotecting procedure to the synthesis of ovine corticotropin releasing factor (oCRF).

AKAJI, KENICHI, NOMIZU, MOTOYOSHI, WATANABE, KAZUHIDE, FUNAKOSHI, SUSUMU, IMURA, HIROO, TSUKADA, TOSHIHIKO, FUKATA, JUNICHI, NAKAMUTA, HIROMICHI, KOIDA, MASAO, FUJII, NOBUTAKA, YAJIMA, HARUAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 1.21 MB

english, 1987

35

Severe Parkinsonism Following Endoscopic Third Ventriculostomy for Non-communicating Hydrocephalus

AKIYAMA, Takenori, TANIZAKI, Yoshio, AKAJI, Kazunori, HIRAGA, Kenji, AKIYAMA, Takekazu, TAKAO, Masaki, OHIRA, Takayuki

Journal:

Neurologia medico-chirurgica

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

36

Survival and recruitment of Sasa kurilensis culms in response to local light conditions in a cool temperate forest

Akaji, Yasuaki, Fujiyoshi, Kyohei, Wu, Chongyang, Hattori, Itsuka, Hirobe, Muneto, Sakamoto, Keiji

Journal:

Journal of Forest Research

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

37

ChemInform Abstract: STUDIES ON PEPTIDES. XCVI. BEHAVIOR OF S-ACETAMIDOMETHYLCYSTEINE SULFOXIDE UNDER DEPROTECTING CONDITIONS IN PEPTIDE SYNTHESIS

YAJIMA, H., AKAJI, K., FUNAKOSHI, S., FUJII, N., IRIE, H.

Journal:

Chemischer Informationsdienst

Year:

1980

File:

PDF, 191 KB

1980

38

ChemInform Abstract: An Aza-Payne Rearrangement-Epoxide Ring Opening Reaction of 2- Aziridinemethanols in a One-Pot Manner: A Regio- and Stereoselective Synthetic Route to Diastereomerically Pure N-Protected 1,2-Amino Alcohols.

T. IBUKA, K. NAKAI, M. AKAJI, H. TAMAMURA, N. FUJII, Y. YAMAMOTO

Journal:

Year:

1997

File:

PDF, 32 KB

1997

39

Studies on Substrate Specificity at PR/p3 Cleavage Site of HTLV-1 Protease

Jeong Kyu Bang, Kenta Teruya, Saburo Aimoto, Hiroyuki Konno, Kazuto Nosaka, Tadashi Tatsumi, Kenichi Akaji

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

40

Genetic regulation mediated by thiamin pyrophosphate-binding motif in Saccharomyces cerevisiae

Kazuto Nosaka, Mari Onozuka, Hiroyuki Konno, Yuko Kawasaki, Hiroshi Nishimura, Mamoru Sano, Kenichi Akaji

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 293 KB

english, 2005

41

Synthesis of an O-acyl isopeptide by using native chemical ligation to efficiently construct a hydrophobic polypeptide

Youhei Sohma, Hitomi Kitamura, Hiroyuki Kawashima, Hironobu Hojo, Masayuki Yamashita, Kenichi Akaji, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

42

Late hemorrhage from persistent pseudoaneurysm in vertebral artery dissection presenting with ischemia: case report

Masachika Sagoh, Yuichi Hirose, Hideki Murakami, Kazunori Akaji, Masateru Katayama, Takuro Hayashi

Journal:

Surgical Neurology

Year:

1999

Language:

english

File:

PDF, 251 KB

english, 1999

43

Synthesis and biological evaluation of a 13N-labeled opioid peptide

Saji, Hideo, Tsutsumi, Daisuke, Kiso, Yoshiaki, Iimuma, Satoshi, Mimoto, Tsutomu, Akaji, Kenichi, Magata, Yasuhiro, Nakamura, Hideo, Kita, Atsuko, Konishi, Junji, Yokoyama, Akira

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1992

Language:

english

File:

PDF, 526 KB

english, 1992

44

Fmoc-based solid-phase peptide synthesis using a new t-alcohol type 4-(1?,1?-dimethyl-1?-hydroxypropyl)phenoxyacetyl handle (DHPP)?resin (Fmoc = fluoren-9-ylmethoxycarbonyl)

Akaji, Kenichi, Kiso, Yoshiaki, Carpino, Louis A.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1990

Language:

english

File:

PDF, 288 KB

english, 1990

45

Structural and Stereochemical Analysis of Some 9-Phenyl-8-N-substituted Thiocarbamoyl-7,8-Diazabicyclo [4.3.0]non-6-enes by NMR and Mass Spectrometric Techniques

Yeşilada, A., Gökhan, N., Bilgin, A., Akaji, M., Shingu, T., Fujita, T.

Journal:

Spectroscopy Letters

Year:

1996

Language:

english

File:

PDF, 526 KB

english, 1996

46

Hemodynamic stress distribution reflects ischemic clinical symptoms of patients with moyamoya disease

Takahashi, Satoshi, Tanizaki, Yoshio, Kimura, Hiroaki, Akaji, Kazunori, Nakazawa, Masaki, Yoshida, Kazunari, Mihara, Ban

Journal:

Clinical Neurology and Neurosurgery

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

47

Racemization-Free Synthesis of C-Terminal Cysteine-Peptide Using 2-Chlorotrityl Resin.

FUJIWARA, Yoichi, AKAJI, Kenichi, KISO, Yoshiaki

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 484 KB

1994

48

Studies on peptides. CXLIV Synthesis and immunological properties of formylmethionyl human adrenocorticotropin.

YASUMURA, KOICHI, OKAMOTO, KENJI, ADACHI, HIDEKI, AKAJI, KENICHI, YAJIMA, HARUAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 646 KB

1986

49

Solid phase total synthesis of callipeltin E isolated from marine sponge Latrunculia sp.

Mari Kikuchi, Kazuto Nosaka, Kenichi Akaji, Hiroyuki Konno

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 622 KB

english, 2011

50

Recent Progress of Thioester Method1

SABURO, A, TERUYA, K, HASEGAWA, K, SATO, T, AKAJI, K, KAWAKAMI, T

Journal:

Chemical Research in Chinese Universities

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

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